Oxford-Led Study Finds New Biopsy Technique to Improve Prostate Cancer Detection
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A study led by the University of Oxford has found that a newer biopsy technique for diagnosing prostate cancer provides more accurate results but is more painful and time-consuming. The research, funded by the National Institute for Health and Care Research (NIHR), involved 1,126 men from across the UK.
The study compared two biopsy methods: the traditional “transrectal” approach and the newer “transperineal” technique, which involves taking samples through the skin. Researchers found that while the transperineal method improves prostate cancer detection, it also requires more time to perform and causes greater discomfort for patients.
Professor Richard Bryant, Chief Investigator from Oxford’s Nuffield Department of Surgical Sciences, highlighted the significance of the study. “Almost 100,000 men in the UK undergo prostate cancer investigations every year. Our findings provide crucial evidence to help urologists and patients decide on the best biopsy method. The transperineal biopsy is superior in detecting clinically meaningful prostate cancer and eliminates the need for antibiotics, reducing the risk of antibiotic resistance. However, it is more painful and takes longer to perform.”
Dr Alastair Lamb, co-lead of the study now at Barts Cancer Institute, Queen Mary University of London, noted that despite widespread adoption of the transperineal biopsy in many hospitals over the last five years, there had been little concrete evidence supporting its superiority. “Our trial confirms that transperineal biopsy is better in some aspects, but not as significantly as previously believed. Moreover, it presents challenges related to patient discomfort and higher costs,” he said.
The study provides valuable insights into improving prostate cancer detection while balancing patient experience and healthcare efficiency. Discussions on optimising biopsy methods in the UK’s healthcare system are expected to continue.
Source: SHIKSHA
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